The Comparison of Onset of Action and Duration of Action for Lidocaine HCl 2% Adrenaline 1:100.000 and Articaine HCl 3% Adrenalin 1:100.000 as Local Anesthetics – Edhi Dhiyauddin – F1O02103

Here is the abstract of Edhi Dhiyauddin's final paper for SKG degree, first step to be a dentist.

(Edhi Dhiyauddin | Fakultas Kedokteran Gigi | Universitas Padjadjaran)

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ABSTRACT

The objective aim of this double blind descriptive-experimental quasi study was to compare the onset of action and the duration of action for Lidocaine HCl 2% adrenaline 1:100.000 and Articaine HCl 4% adrenaline 1:100.000.
As the sample used 30 persons, 15 persons of them were injected with Lidocaine HCl 2% adrenaline 1:100.000 and the other 15 persons were injected with Articaine HCl 4% adrenaline 1:100.000. The onset of action and the duration of action were measured with the sensation of pharestesia on the tongue (Lingual nerve) and on the low lip (Alveolaris inferior nerve) after block injection on the right of mandibula.
The results of this study showed that the average of onset of action Lidocaine HCl 2% adrenaline 1:100.000 on the Lingual nerve was 1 minute 55 seconds, meanwhile for Articaine HCl 4% adrenaline 1:100.000 was 1 minute 14 seconds. The duration of action Lidocaine HCl 2% adrenaline 1:100.000 on the Lingual nerve was 227,87 minutes and for Articaine HCl 4% adrenaline 1:100.000 was 300,2 minutes. The average of the onset of action Lidocaine HCl 2% adrenaline 1:100.000 on the Alveolaris inferior nerve was 1 minute 59 seconds and for Articaine HCl 4% adrenaline 1:100.000 was 1 minute 36 seconds. The average of the duration of action Lidocaine HCl 2% adrenaline 1:100.000 on the Aveolaris inferior nerve was 239,93 minutes, meanwhile for Articaine HCl 4% adrenaline 1:100.000 was 317,93 minues. The normal distribution data was tested with t-student test and for the non-normal distribution data was tested with Mann-Whitney U-test. Both tests showed significant difference for the duration of action and showed non significant difference for the onset of action for Lidocaine HCl 2% adrenaline 1:100.000 and Articaine HCl 4% adrenaline 1:100.000.
The conclusion of this study that onset of action and duration of action Articaine 4% adrenaline 1:100.000 was faster and longer compared to Lidocaine HCl 2% adrenaline 1:100.000

Keywords : lidocaine HCl 2% adrenaline 1:100.000, articaine HCl 4% adrenaline 1:100.000, onset of action, duration of action